Three point six is the heroin formula. This drug transformed the multi-ethnic district of San Salvario, in the center of Turin, into a powder keg always on the verge of exploding. The organized crime controls prostitution and drug dealing, and governs the lives of the inhabitants whose stories are intertwined. Two friends, Silvio and Dante, close to each other since childhood, one a corrupt policeman, the other a criminal, are doing business together while they are divided by love for the same woman.